EFFECT OF PROPRANOLOL AND CARVEDILOL ON HEMODYNAMICS BY PATIENTS WITH ATRIAL FIBRILLATION WITH TACHYSYSTOLE DURING DRUG TEST

Bartosh Fyodor Leonidovich, Candidate of medical sciences, head of department of functional diagnostics, Federal Center of Cardiovascular Surgery (Penza), fbartosh@km.ru
Smirnova Tatyana Petrovna, Postgraduate student, Penza Institute of Advanced Medical Studies, tsmirnova75@mail.ru
Bartosh Leonid Fyodorovich, Doctor of medical sciences, professor, head of sub-department of therapeutics, general practice, endocrinology and gastroenterology, Penza Institute of Advanced Medical Studies, rodino091@rambler.ru

616.125-008.318.1:615.3

The study compares hemodynamic effects of Carvedilol and Propranolol in patients with permanent form of atrial fibrillation with chronic heart failure by execution of medicinal test for drug selection. 30 patients (13 women and 17 men) were examined. The average age of patients with signs of chronic heart failure of II functional class by NYHA is 60 ± 8,5 years. All patients were subject to comparative assessment of hemodynamic parameters changes under the influence of the above mentioned drugs. It is shown, that application of Propranolol and Carvedilol leads to unidirectional shifts of cardio hemodynamic parameters. But Carvedilol causes more evident decrease of blood pressure and less evident decrease of heart rate than Pro-pranolol.

atrial fibrillation, chronic heart failure, cardio hemodynamic, Carvedilol, Propranolol.